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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-9-21
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pubmed:abstractText |
Thymopoiesis requires thymocyte-stroma interactions and proteases that promote cell migration by degrading extracellular matrix and releasing essential cytokines and chemokines. A role for several members of the A Disintegrin and Metalloprotease (ADAM) family in T cell development has been reported in the past.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e12766
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pubmed:meshHeading |
pubmed-meshheading:20856819-ADAM Proteins,
pubmed-meshheading:20856819-Animals,
pubmed-meshheading:20856819-Antigens, CD,
pubmed-meshheading:20856819-Cell Differentiation,
pubmed-meshheading:20856819-Cell Movement,
pubmed-meshheading:20856819-Cell Proliferation,
pubmed-meshheading:20856819-Female,
pubmed-meshheading:20856819-Male,
pubmed-meshheading:20856819-Membrane Proteins,
pubmed-meshheading:20856819-Mice,
pubmed-meshheading:20856819-Mice, Inbred C57BL,
pubmed-meshheading:20856819-Mice, Knockout,
pubmed-meshheading:20856819-T-Lymphocytes,
pubmed-meshheading:20856819-Thymus Gland
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pubmed:year |
2010
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pubmed:articleTitle |
Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity.
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pubmed:affiliation |
The Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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