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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
The response to the anticoagulant drug warfarin is greatly affected by genetic polymorphisms in the VKORC1 and CYP2C9 genes. Genotyping these polymorphisms has been shown to be important in reducing the time of the trial and error process for finding the maintenance dose of warfarin thus reducing the risk of adverse effects of the drug.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1873-3492
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
412
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-85
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pubmed:dateRevised |
2011-10-6
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pubmed:meshHeading |
pubmed-meshheading:20854800-Anticoagulants,
pubmed-meshheading:20854800-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:20854800-DNA Helicases,
pubmed-meshheading:20854800-Genotype,
pubmed-meshheading:20854800-Humans,
pubmed-meshheading:20854800-Mixed Function Oxygenases,
pubmed-meshheading:20854800-Nucleic Acid Amplification Techniques,
pubmed-meshheading:20854800-Polymorphism, Single Nucleotide,
pubmed-meshheading:20854800-Reference Standards,
pubmed-meshheading:20854800-Reproducibility of Results,
pubmed-meshheading:20854800-Temperature,
pubmed-meshheading:20854800-Thermoanaerobacter,
pubmed-meshheading:20854800-Time Factors,
pubmed-meshheading:20854800-Warfarin
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pubmed:year |
2011
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pubmed:articleTitle |
Genotyping three SNPs affecting warfarin drug response by isothermal real-time HDA assays.
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pubmed:affiliation |
BioHelix Corporation, Beverly MA 01915, USA. li@biohelix.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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