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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2011-1-21
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pubmed:abstractText |
p45 NF-E2 is a bZIP transcription factor crucial for thrombopoiesis, as indicated by the fact that loss of p45 NF-E2 function results in dramatic embryonic lethal thrombopoietic defects and its overexpression boosts platelet release.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 International Society on Thrombosis and Haemostasis.
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2542-53
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pubmed:meshHeading |
pubmed-meshheading:20854373-Active Transport, Cell Nucleus,
pubmed-meshheading:20854373-Animals,
pubmed-meshheading:20854373-Blood Platelets,
pubmed-meshheading:20854373-Bone Marrow Cells,
pubmed-meshheading:20854373-COS Cells,
pubmed-meshheading:20854373-Cell Nucleus,
pubmed-meshheading:20854373-Cercopithecus aethiops,
pubmed-meshheading:20854373-DNA,
pubmed-meshheading:20854373-Humans,
pubmed-meshheading:20854373-Luciferases,
pubmed-meshheading:20854373-Megakaryocytes,
pubmed-meshheading:20854373-Mice,
pubmed-meshheading:20854373-Mice, Inbred C57BL,
pubmed-meshheading:20854373-Models, Biological,
pubmed-meshheading:20854373-NF-E2 Transcription Factor, p45 Subunit,
pubmed-meshheading:20854373-Nuclear Localization Signals,
pubmed-meshheading:20854373-Protein Binding,
pubmed-meshheading:20854373-Thrombopoiesis,
pubmed-meshheading:20854373-Transcriptional Activation
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pubmed:year |
2010
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pubmed:articleTitle |
A monopartite sequence is essential for p45 NF-E2 nuclear translocation, transcriptional activity and platelet production.
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pubmed:affiliation |
Centre for Vascular Research, University of New South Wales, Sydney, New South Wales, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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