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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-1
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pubmed:abstractText |
Hypoxia is a prominent feature in rheumatoid arthritis (RA) synovium. However, its contribution to the pathogenesis of RA remains unclear. We undertook this study to systematically characterize the changes in gene expression induced by hypoxia in synovial fibroblasts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1529-0131
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 by the American College of Rheumatology.
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3584-94
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pubmed:meshHeading |
pubmed-meshheading:20848564-Adenylate Kinase,
pubmed-meshheading:20848564-Arthritis, Rheumatoid,
pubmed-meshheading:20848564-Cell Hypoxia,
pubmed-meshheading:20848564-Cells, Cultured,
pubmed-meshheading:20848564-Cyclooxygenase 2,
pubmed-meshheading:20848564-Energy Metabolism,
pubmed-meshheading:20848564-Fibroblasts,
pubmed-meshheading:20848564-Gene Expression Profiling,
pubmed-meshheading:20848564-Humans,
pubmed-meshheading:20848564-Hypoxia-Inducible Factor 1,
pubmed-meshheading:20848564-Immunity,
pubmed-meshheading:20848564-Inflammation,
pubmed-meshheading:20848564-Microarray Analysis,
pubmed-meshheading:20848564-Neovascularization, Physiologic,
pubmed-meshheading:20848564-Signal Transduction,
pubmed-meshheading:20848564-Synovial Membrane,
pubmed-meshheading:20848564-Vascular Endothelial Growth Factor A
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pubmed:year |
2010
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pubmed:articleTitle |
The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia.
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pubmed:affiliation |
Instituto de Investigación Hospital 12 de Octubre, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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