Source:http://linkedlifedata.com/resource/pubmed/id/20846583
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2010-9-17
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| pubmed:abstractText |
The prevalence of diarrheagenic Escherichia coli (DEC) in children under 5 years was studied in children with diarrhea and controls in South India. Four polymerase chain reaction (PCR) "schemes" were used to detect genes of the 6 pathotypes of DEC. In 394 children with diarrhea, 203 (52%) DEC infections were found. Among the 198 controls, 126 (63%) DEC infections were found. Enteroaggregative E. coli was the most common pathotype by multiplex PCR both in cases (58, 14.7%) and controls (47, 23.7%), followed by enteropathogenic E. coli seen in 10% cases and 8% of controls. Enterotoxigenic E. coli (ETEC), enterohemorrhagic E. coli (EHEC), enteroinvasive E. coli (EIEC), and diffusely adherent E. coli (DAEC) were found in 4.1%, 2.0%, 1.0%, and 0.5% of cases, respectively. ETEC was found in 2.5% of controls, but EHEC, EIEC, and DAEC were not detected. Overall, no single assay worked well, but by discounting genes with a pathogenicity index of less than 1, it was possible to use the PCR assays to identify DEC in 75/394 (19%) cases and 12/198 (6.1%) controls, while mixed infection could be identified in 8/394 (2%) cases and 2/198 (1%) controls.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
1879-0070
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| pubmed:author |
pubmed-author:AjjampurSitara Swarna RaoSS,
pubmed-author:ChandraboseGunasekaranG,
pubmed-author:ChidambaramDivyaD,
pubmed-author:KangGagandeepG,
pubmed-author:RajanDeva PrasannaDP,
pubmed-author:RajendranPriyaP,
pubmed-author:SamuelPrasannaP,
pubmed-author:SarkarRajivR,
pubmed-author:ThangarajBhuvaneswariB
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| pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:volume |
68
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
117-22
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| pubmed:meshHeading |
pubmed-meshheading:20846583-Child, Preschool,
pubmed-meshheading:20846583-DNA, Bacterial,
pubmed-meshheading:20846583-Diarrhea,
pubmed-meshheading:20846583-Enterohemorrhagic Escherichia coli,
pubmed-meshheading:20846583-Enteropathogenic Escherichia coli,
pubmed-meshheading:20846583-Enterotoxigenic Escherichia coli,
pubmed-meshheading:20846583-Escherichia coli,
pubmed-meshheading:20846583-Escherichia coli Infections,
pubmed-meshheading:20846583-Feces,
pubmed-meshheading:20846583-Genetic Variation,
pubmed-meshheading:20846583-Humans,
pubmed-meshheading:20846583-India,
pubmed-meshheading:20846583-Infant,
pubmed-meshheading:20846583-Infant, Newborn,
pubmed-meshheading:20846583-Molecular Epidemiology,
pubmed-meshheading:20846583-Polymerase Chain Reaction,
pubmed-meshheading:20846583-Prevalence
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| pubmed:year |
2010
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| pubmed:articleTitle |
Pathotypes of diarrheagenic Escherichia coli in children attending a tertiary care hospital in South India.
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| pubmed:affiliation |
Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India.
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| pubmed:publicationType |
Journal Article
|