Linked Life Data

20843981

Source:http://linkedlifedata.com/resource/pubmed/id/20843981

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-11-30
pubmed:abstractText
Childhood obesity strongly predisposes to some adult diseases. Recently, genome-wide association (GWA) studies in Caucasians identified multiple single nucleotide polymorphisms (SNPs) associated with BMI and obesity. The associations of those SNPs with BMI and obesity among other ethnicities are not fully described, especially in children. Among those previously identified SNPs, we selected six (rs7138803, rs1805081, rs6499640, rs17782313, rs6265, and rs10938397, in or near obesity-related genes FAIM2, NPC1, FTO, MC4R, BDNF, and GNPDA2, respectively) because of the relatively high minor allele frequencies in Chinese individuals and tested the associations of the SNPs with BMI and obesity in Chinese children.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1939-327X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3085-9
pubmed:meshHeading
pubmed-meshheading:20843981-Adolescent, pubmed-meshheading:20843981-Alleles, pubmed-meshheading:20843981-Asian Continental Ancestry Group, pubmed-meshheading:20843981-Body Mass Index, pubmed-meshheading:20843981-Brain-Derived Neurotrophic Factor, pubmed-meshheading:20843981-Carrier Proteins, pubmed-meshheading:20843981-Child, pubmed-meshheading:20843981-European Continental Ancestry Group, pubmed-meshheading:20843981-Female, pubmed-meshheading:20843981-Gene Frequency, pubmed-meshheading:20843981-Genome-Wide Association Study, pubmed-meshheading:20843981-Genotype, pubmed-meshheading:20843981-Humans, pubmed-meshheading:20843981-Male, pubmed-meshheading:20843981-Membrane Glycoproteins, pubmed-meshheading:20843981-Obesity, pubmed-meshheading:20843981-Overweight, pubmed-meshheading:20843981-Polymorphism, Single Nucleotide, pubmed-meshheading:20843981-Regression Analysis, pubmed-meshheading:20843981-Risk Factors
pubmed:year
2010
pubmed:articleTitle
Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children.
pubmed:affiliation
Department of Epidemiology, Capital Institute of Pediatrics, Beijing, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't