Lung squamous cell carcinomas (SqCCs) occur at higher rates following arsenic exposure. Somatic DNA copy-number alterations (CNAs) are understood to be critical drivers in several tumour types. We have assembled a rare panel of lung tumours from a population with chronic arsenic exposure, including SqCC tumours from patients with no smoking history.
Department of Molecular and Cell Biology, Faculty of Medicine, Biomedical Sciences Institute, University of Chile, Independencia 1027, Santiago 8380453, Chile. vmartinez@med.uchile.cl