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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-10
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pubmed:abstractText |
single nucleotide polymorphisms (SNPs) in the genes for catecholamine-O-methyltransferase (COMT), ?-opioid receptor and GTP cyclohydrolase (GCH1) have been linked to acute and chronic pain states. COMT polymorphisms are associated with experimental pain sensitivity and a chronic pain state. No such association has been identified perioperatively. We carried out a prospective observational clinical trial to examine associations between these parameters and the development of postoperative pain in patients undergoing third molar (M3) extraction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1536-5409
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
93-101
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pubmed:meshHeading |
pubmed-meshheading:20842020-Catechol O-Methyltransferase,
pubmed-meshheading:20842020-Female,
pubmed-meshheading:20842020-Genetic Association Studies,
pubmed-meshheading:20842020-Genetic Predisposition to Disease,
pubmed-meshheading:20842020-Humans,
pubmed-meshheading:20842020-Ireland,
pubmed-meshheading:20842020-Male,
pubmed-meshheading:20842020-Molar, Third,
pubmed-meshheading:20842020-Pain, Postoperative,
pubmed-meshheading:20842020-Pain Measurement,
pubmed-meshheading:20842020-Polymorphism, Genetic,
pubmed-meshheading:20842020-Polymorphism, Single Nucleotide,
pubmed-meshheading:20842020-Prevalence,
pubmed-meshheading:20842020-Risk Assessment,
pubmed-meshheading:20842020-Risk Factors,
pubmed-meshheading:20842020-Tooth Extraction,
pubmed-meshheading:20842020-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Catecholamine-o-methyltransferase polymorphisms are associated with postoperative pain intensity.
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pubmed:affiliation |
Departments of Anaesthesia and Intensive Care Medicine, University College Cork, Ireland. peterjohnlee@hotmail.com
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pubmed:publicationType |
Journal Article
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