rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19-22
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pubmed:dateCreated |
2010-11-5
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pubmed:abstractText |
Epilepsy as well as chronic use of most antiepileptic drugs predisposes to cognitive impairment. Curcumin has been reported to possess antioxidant, anticonvulsant as well as neuroprotective potential. Hence, this study was conducted to evaluate the effect of curcumin against seizures, cognitive impairment and oxidative stress in pentylenetetrazole-induced kindling in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
596-603
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pubmed:meshHeading |
pubmed-meshheading:20840851-Administration, Oral,
pubmed-meshheading:20840851-Animals,
pubmed-meshheading:20840851-Anticonvulsants,
pubmed-meshheading:20840851-Antioxidants,
pubmed-meshheading:20840851-Avoidance Learning,
pubmed-meshheading:20840851-Cognition Disorders,
pubmed-meshheading:20840851-Curcumin,
pubmed-meshheading:20840851-Disease Models, Animal,
pubmed-meshheading:20840851-Dose-Response Relationship, Drug,
pubmed-meshheading:20840851-Glutathione,
pubmed-meshheading:20840851-Kindling, Neurologic,
pubmed-meshheading:20840851-Male,
pubmed-meshheading:20840851-Malondialdehyde,
pubmed-meshheading:20840851-Maze Learning,
pubmed-meshheading:20840851-Oxidative Stress,
pubmed-meshheading:20840851-Pentylenetetrazole,
pubmed-meshheading:20840851-Rats,
pubmed-meshheading:20840851-Rats, Wistar,
pubmed-meshheading:20840851-Seizures
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pubmed:year |
2010
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pubmed:articleTitle |
Protective effect of curcumin against seizures and cognitive impairment in a pentylenetetrazole-kindled epileptic rat model.
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pubmed:affiliation |
Neuropharmacology Laboratory, Department of Pharmacology, All India Institute of Medical Sciences, New Delhi-110029, India.
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pubmed:publicationType |
Journal Article
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