Linked Life Data

20839495

Source:http://linkedlifedata.com/resource/pubmed/id/20839495

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-9-15
pubmed:abstractText
Recent studies suggest that exchange of macrophage phenotype (M1/M2) in adipose tissue is associated with chronic low-grade inflammation in obesity. M1 macrophages enhance a chronic inflammatory state in adipose tissues, whereas M2 macrophages inhibit it. Although exercise training might inhibit pro-inflammatory cytokine gene expression in adipose tissue, it remains unclear whether exercise training affects the phenotypic switch of macrophage polarization in adipose tissue. Therefore, we inveStigated the effect of exercise training on the macrophage phenotypic switch in adipose tissue in high-fat-induced obese mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1077-5552
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-18
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice.
pubmed:affiliation
Graduate School of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't