rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
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pubmed:dateCreated |
2010-9-14
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pubmed:abstractText |
Histopathological studies and animal models suggest that hippocampal subfields may be differently affected by aging, Alzheimer's disease (AD), and other diseases. High-resolution images at 4 Tesla depict details of the internal structure of the hippocampus allowing for in vivo volumetry of different subfields. The aims of this study were as follows: (1) to determine patterns of volume loss in hippocampal subfields in normal aging, AD, and amnestic mild cognitive impairment (MCI). (2) To determine if measurements of hippocampal subfields provide advantages over total hippocampal volume for differentiation between groups.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1097-0193
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pubmed:author |
|
pubmed:copyrightInfo |
Hum Brain Mapp, 2010. © 2010 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1339-47
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pubmed:meshHeading |
pubmed-meshheading:20839293-Aged,
pubmed-meshheading:20839293-Aged, 80 and over,
pubmed-meshheading:20839293-Alzheimer Disease,
pubmed-meshheading:20839293-Atrophy,
pubmed-meshheading:20839293-Cognition Disorders,
pubmed-meshheading:20839293-Female,
pubmed-meshheading:20839293-Hippocampus,
pubmed-meshheading:20839293-Humans,
pubmed-meshheading:20839293-Image Interpretation, Computer-Assisted,
pubmed-meshheading:20839293-Magnetic Resonance Imaging,
pubmed-meshheading:20839293-Male,
pubmed-meshheading:20839293-Middle Aged
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pubmed:year |
2010
|
pubmed:articleTitle |
Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease.
|
pubmed:affiliation |
Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|