Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1991-5-10
|
pubmed:abstractText |
Purified rat islets were dissociated into single-cell suspension with an EDTA-Trypsin treatment. During a stationary culture in vitro the islet cells reassociated forming aggregates (neoislets). Electron microscopy revealed that the aggregates consisted mostly of beta-cells and not numerous alpha-cells. They showed a good insulin-secreting capacity and were able to increase insulin release in response to glucose plus theophylline. The lack of passenger leukocytes makes the neoislets particularly suited for experimental and clinical transplantation.
|
pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0365-9615
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
110
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
650-3
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2083373-Animals,
pubmed-meshheading:2083373-Cells, Cultured,
pubmed-meshheading:2083373-Culture Media,
pubmed-meshheading:2083373-Glucose,
pubmed-meshheading:2083373-Insulin,
pubmed-meshheading:2083373-Islets of Langerhans,
pubmed-meshheading:2083373-Islets of Langerhans Transplantation,
pubmed-meshheading:2083373-Male,
pubmed-meshheading:2083373-Rats,
pubmed-meshheading:2083373-Rats, Inbred Strains,
pubmed-meshheading:2083373-Theophylline
|
pubmed:year |
1990
|
pubmed:articleTitle |
[Aggregates of islet cells, their structure and insulin-producing activity during cultivation in vitro].
|
pubmed:publicationType |
Journal Article,
English Abstract
|