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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-10
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pubmed:abstractText |
Abdominal aortic aneurysm (AAA) is a complex vascular disease characterized by matrix degradation and inflammation and is a major cause of mortality in older men. Specific interventions that prevent AAA progression remain to be identified. In this study, we tested the hypothesis that Group X secretory phospholipase A(2) (GX sPLA(2)), an enzyme implicated in inflammatory processes, mediates AAA.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
214
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
58-64
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pubmed:dateRevised |
2011-9-15
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pubmed:meshHeading |
pubmed-meshheading:20833395-Angiotensin II,
pubmed-meshheading:20833395-Animals,
pubmed-meshheading:20833395-Aorta, Abdominal,
pubmed-meshheading:20833395-Aortic Aneurysm, Abdominal,
pubmed-meshheading:20833395-Apolipoproteins E,
pubmed-meshheading:20833395-Blood Pressure,
pubmed-meshheading:20833395-Group X Phospholipases A2,
pubmed-meshheading:20833395-Humans,
pubmed-meshheading:20833395-Inflammation,
pubmed-meshheading:20833395-Interleukins,
pubmed-meshheading:20833395-Metalloproteases,
pubmed-meshheading:20833395-Mice,
pubmed-meshheading:20833395-Mice, Inbred C57BL,
pubmed-meshheading:20833395-Mice, Transgenic
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pubmed:year |
2011
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pubmed:articleTitle |
Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice.
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pubmed:affiliation |
Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY 40536-0200, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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