Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-9-13
pubmed:abstractText
Pheochromocytoma and paraganglioma are rare tumors of adrenals as well as the sympathetic and parasympathetic paraganglia. Clinical presentation of these tumors depends on localization, secretory profile and malignant potential. Four distinct syndromes--PGL1-4--are related to mutations in the succinate dehydrogenase gene--mitochondrial complex involved in electron transfer and Krebs cycle. Here we describe etiology, genetics, as well as clinical aspects of SDH-related tumors. We also describe recent discoveries in HIF-related pathway of tumorigenesis and mutations in new SDH-related genes that have improved our understanding of this disease.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-11062460, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-11404820, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-11605159, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-12000816, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-12213855, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-12364472, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-12658451, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-12811540, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-14062129, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15328326, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15362582, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15369446, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15652751, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15718487, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15953133, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-15987702, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16249420, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16266984, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16314641, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16317055, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16912137, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-16951005, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17102077, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17102084, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17102103, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17102115, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17200167, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17227803, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17237836, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17557926, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-17973943, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-18212813, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-18334619, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-18840642, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19075037, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19092153, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19391076, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19454582, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19576851, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19636009, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19694582, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19763184, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19825962, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-19897674, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-20071235, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-20130071, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-2574254, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-3369315, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-3395037, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-6286462, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-9050342, http://linkedlifedata.com/resource/pubmed/commentcorrection/20833333-9837811
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1532-1908
pubmed:author
pubmed:copyrightInfo
Published by Elsevier Ltd.
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
415-24
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
SDH-related pheochromocytoma and paraganglioma.
pubmed:affiliation
Division of Endocrinology and Metabolism, University of Arkansas for Medical Sciences, ACRC, Suite 817, 4301 West Markham St., Little Rock, AR 72205-7199, United States. vkantorovich@uams.edu
pubmed:publicationType
Journal Article, Review