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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
LIM-domain-binding (Ldb) proteins have been demonstrated to be essential not only to key embryonic developmental processes but also to carcinogenesis. We have previously demonstrated Ldb1 to be of high biological and developmental relevance, as a targeted deletion of the Ldb1 gene in mice results in an embryonic lethal and pleiotropic phenotype.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010. Published by Elsevier B.V.
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pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1078-84
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20828852-Animals,
pubmed-meshheading:20828852-Apoptosis,
pubmed-meshheading:20828852-Base Sequence,
pubmed-meshheading:20828852-DNA-Binding Proteins,
pubmed-meshheading:20828852-LIM Domain Proteins,
pubmed-meshheading:20828852-Liver,
pubmed-meshheading:20828852-Liver Neoplasms, Experimental,
pubmed-meshheading:20828852-Mice,
pubmed-meshheading:20828852-Mice, Inbred C57BL,
pubmed-meshheading:20828852-Mice, Knockout,
pubmed-meshheading:20828852-Mice, Transgenic,
pubmed-meshheading:20828852-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20828852-RNA, Messenger,
pubmed-meshheading:20828852-RNA, Neoplasm
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pubmed:year |
2010
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pubmed:articleTitle |
Liver-specific Ldb1 deletion results in enhanced liver cancer development.
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pubmed:affiliation |
Department of Medicine I, Johannes Gutenberg University, Mainz, Germany. teufel@uni-mainz.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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