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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
Interferon-?-1b (IFN?-1b) has been used to prevent exacerbation of relapsing-remitting multiple sclerosis (RRMS) including optic-spinal multiple sclerosis (OSMS) in Japan. We encountered 2 patients with OSMS with unexpectedly severe exacerbation soon after the initiation of IFN?-1b therapy. The experience urged us to retrospectively review the patients with RRMS who had been treated with IFN?-1b to identify similar cases.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1526-632X
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pubmed:author |
pubmed-author:DatiTT,
pubmed-author:GotoJJ,
pubmed-author:HasegawaMM,
pubmed-author:HashidaHH,
pubmed-author:HashimotoKK,
pubmed-author:HatanakaYY,
pubmed-author:IwataAA,
pubmed-author:KomiyaTT,
pubmed-author:NakaseHH,
pubmed-author:SakuraiYY,
pubmed-author:ShimizuJJ,
pubmed-author:ShimizuTT,
pubmed-author:SugimotoII,
pubmed-author:TakatsuMM,
pubmed-author:TsujiSS,
pubmed-author:UesakaYY
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1423-7
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pubmed:dateRevised |
2011-8-26
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pubmed:meshHeading |
pubmed-meshheading:20826711-Adjuvants, Immunologic,
pubmed-meshheading:20826711-Adult,
pubmed-meshheading:20826711-Aquaporin 4,
pubmed-meshheading:20826711-Asian Continental Ancestry Group,
pubmed-meshheading:20826711-Disability Evaluation,
pubmed-meshheading:20826711-Female,
pubmed-meshheading:20826711-Humans,
pubmed-meshheading:20826711-Interferon-beta,
pubmed-meshheading:20826711-Japan,
pubmed-meshheading:20826711-Magnetic Resonance Imaging,
pubmed-meshheading:20826711-Male,
pubmed-meshheading:20826711-Middle Aged,
pubmed-meshheading:20826711-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:20826711-Neuromyelitis Optica,
pubmed-meshheading:20826711-Optic Nerve,
pubmed-meshheading:20826711-Retrospective Studies,
pubmed-meshheading:20826711-Spinal Cord
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pubmed:year |
2010
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pubmed:articleTitle |
IFN?-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum.
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pubmed:affiliation |
Department of Neurology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. jshimizu-tky@umin.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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