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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-12-6
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pubmed:abstractText |
Thyroperoxidase (TPO) and dual oxidase (DUOX) are present at the apical membrane of thyrocytes, where TPO catalyzes thyroid hormone biosynthesis in the presence of H2O2 produced by DUOX. Both enzymes are colocalized and associated, but the consequences of this interaction remain obscure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Autoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/Catalase,
http://linkedlifedata.com/resource/pubmed/chemical/DUOX2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide,
http://linkedlifedata.com/resource/pubmed/chemical/Iodide Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Iron-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/TPO protein, human
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1945-7197
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pubmed:author |
pubmed-author:Ameziane-el HassaniRabiiR,
pubmed-author:BidartJean-MichelJM,
pubmed-author:BoufraqechMyriemM,
pubmed-author:DupuyCorinneC,
pubmed-author:FortunatoRodrigo SoaresRS,
pubmed-author:Lagente-ChevallierOdileO,
pubmed-author:Lima de SouzaElaine CristinaEC,
pubmed-author:SchlumbergerMartinM,
pubmed-author:TalbotMoniqueM,
pubmed-author:WeyemiUrbainU,
pubmed-author:de CarvalhoDenise PiresDP
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pubmed:issnType |
Electronic
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5403-11
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pubmed:meshHeading |
pubmed-meshheading:20826581-Autoantigens,
pubmed-meshheading:20826581-Catalase,
pubmed-meshheading:20826581-Cell Membrane,
pubmed-meshheading:20826581-Flow Cytometry,
pubmed-meshheading:20826581-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20826581-HEK293 Cells,
pubmed-meshheading:20826581-Humans,
pubmed-meshheading:20826581-Hydrogen Peroxide,
pubmed-meshheading:20826581-Iodide Peroxidase,
pubmed-meshheading:20826581-Iron-Binding Proteins,
pubmed-meshheading:20826581-Kidney,
pubmed-meshheading:20826581-NADPH Oxidase,
pubmed-meshheading:20826581-Oligonucleotides, Antisense,
pubmed-meshheading:20826581-Oxidoreductases,
pubmed-meshheading:20826581-Transfection
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pubmed:year |
2010
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pubmed:articleTitle |
Functional consequences of dual oxidase-thyroperoxidase interaction at the plasma membrane.
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pubmed:affiliation |
Instituto de Biofisica Carlos Chagas Filho, CCS-Bloc G-Cidade Universitaria, Rio de Janeiro, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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