|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2011-2-3
|
|
pubmed:abstractText |
Insulin resistance, a condition associated with type 2 diabetes mellitus, results from the interaction of environmental and genetic factors. The aim of this study was to explore the influence of the G972R polymorphism at the insulin receptor substrate 1 gene on insulin sensitivity in a healthy young population. Furthermore, we examined whether the presence of this single nucleotide polymorphism (SNP; GR or GG) interacts with dietary fat to modulate insulin sensitivity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Carbohydrates,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Nonesterified,
http://linkedlifedata.com/resource/pubmed/chemical/IRS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin Receptor Substrate Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/lipoprotein cholesterol
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1613-4133
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
55
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
328-35
|
|
pubmed:meshHeading |
pubmed-meshheading:20824664-Adult,
pubmed-meshheading:20824664-Blood Glucose,
pubmed-meshheading:20824664-Body Mass Index,
pubmed-meshheading:20824664-Cholesterol,
pubmed-meshheading:20824664-Cross-Over Studies,
pubmed-meshheading:20824664-Diet, Fat-Restricted,
pubmed-meshheading:20824664-Dietary Carbohydrates,
pubmed-meshheading:20824664-Dietary Fats,
pubmed-meshheading:20824664-Fatty Acids, Monounsaturated,
pubmed-meshheading:20824664-Fatty Acids, Nonesterified,
pubmed-meshheading:20824664-Female,
pubmed-meshheading:20824664-Genetic Association Studies,
pubmed-meshheading:20824664-Heterozygote,
pubmed-meshheading:20824664-Humans,
pubmed-meshheading:20824664-Insulin Receptor Substrate Proteins,
pubmed-meshheading:20824664-Insulin Resistance,
pubmed-meshheading:20824664-Lipoproteins,
pubmed-meshheading:20824664-Male,
pubmed-meshheading:20824664-Polymorphism, Single Nucleotide,
pubmed-meshheading:20824664-Spain,
pubmed-meshheading:20824664-Young Adult
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
The insulin sensitivity response is determined by the interaction between the G972R polymorphism of the insulin receptor substrate 1 gene and dietary fat.
|
|
pubmed:affiliation |
Lipids and Atherosclerosis Unit, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba and Ciber Fisiopatologia Obesidad y Nutricion, Instituto Salud Carlos III, Córdoba, Spain.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|
