Source:http://linkedlifedata.com/resource/pubmed/id/20824058
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2010-9-8
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pubmed:abstractText |
Circadian rhythms govern many aspects of physiology and behavior including cognitive processes. Components of neural circuits involved in learning and memory, e.g., the amygdala and the hippocampus, exhibit circadian rhythms in gene expression and signaling pathways. The functional significance of these rhythms is still not understood. In the present study, we sought to determine the impact of transiently disrupting the circadian system by shifting the light/dark (LD) cycle. Such "jet lag" treatments alter daily rhythms of gene expression that underlie circadian oscillations as well as disrupt the synchrony between the multiple oscillators found within the body.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:meshHeading |
pubmed-meshheading:20824058-Animals,
pubmed-meshheading:20824058-Circadian Rhythm,
pubmed-meshheading:20824058-Fear,
pubmed-meshheading:20824058-Humans,
pubmed-meshheading:20824058-Light,
pubmed-meshheading:20824058-Male,
pubmed-meshheading:20824058-Memory,
pubmed-meshheading:20824058-Mice,
pubmed-meshheading:20824058-Mice, Inbred C57BL,
pubmed-meshheading:20824058-Models, Animal,
pubmed-meshheading:20824058-Photoperiod
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pubmed:year |
2010
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pubmed:articleTitle |
Rapid changes in the light/dark cycle disrupt memory of conditioned fear in mice.
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pubmed:affiliation |
Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, California, United States of America.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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