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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-11-30
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pubmed:abstractText |
The clinical effectiveness of parenterally-administered glucagon-like peptide-1 (GLP-1) mimetics to improve glucose control in patients suffering from type 2 diabetes strongly supports discovery pursuits aimed at identifying and developing orally active, small molecule GLP-1 receptor agonists. The purpose of these studies was to identify and characterize novel nonpeptide agonists of the GLP-1 receptor.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Gastric Inhibitory Polypeptide,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon-Like Peptide 1,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Luciferases,
http://linkedlifedata.com/resource/pubmed/chemical/Parathyroid Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoactive Intestinal Peptide,
http://linkedlifedata.com/resource/pubmed/chemical/glucagon-like peptide receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1939-327X
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pubmed:author |
pubmed-author:BrennerMartin BMB,
pubmed-author:CaoJulia X CJX,
pubmed-author:CoghlanMichael JMJ,
pubmed-author:CoxAmy LAL,
pubmed-author:FarbThomas BTB,
pubmed-author:FicorilliJamesJ,
pubmed-author:Gutierrez SanfelicianoSonia MariaSM,
pubmed-author:MichaelM DodsonMD,
pubmed-author:ShowalterAaron DAD,
pubmed-author:SloopKyle WKW,
pubmed-author:TebbeMark JMJ,
pubmed-author:ValasekKathleenK,
pubmed-author:WillardFrancis SFS
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3099-107
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20823098-Animals,
pubmed-meshheading:20823098-Cyclic AMP,
pubmed-meshheading:20823098-Gastric Inhibitory Polypeptide,
pubmed-meshheading:20823098-Genes, Reporter,
pubmed-meshheading:20823098-Glucagon,
pubmed-meshheading:20823098-Glucagon-Like Peptide 1,
pubmed-meshheading:20823098-Glucose Tolerance Test,
pubmed-meshheading:20823098-Humans,
pubmed-meshheading:20823098-Insulin,
pubmed-meshheading:20823098-Islets of Langerhans,
pubmed-meshheading:20823098-Luciferases,
pubmed-meshheading:20823098-Male,
pubmed-meshheading:20823098-Parathyroid Hormone,
pubmed-meshheading:20823098-Rats,
pubmed-meshheading:20823098-Rats, Sprague-Dawley,
pubmed-meshheading:20823098-Receptors, Glucagon,
pubmed-meshheading:20823098-Vasoactive Intestinal Peptide
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pubmed:year |
2010
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pubmed:articleTitle |
Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets.
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pubmed:affiliation |
Endocrine Discovery, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA. sloop_kyle_w@lilly.com
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pubmed:publicationType |
Journal Article
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