|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0013216,
umls-concept:C0017428,
umls-concept:C0017636,
umls-concept:C0030705,
umls-concept:C0871261,
umls-concept:C1522449,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1709016,
umls-concept:C2603343,
umls-concept:C2911692
|
|
pubmed:dateCreated |
2010-9-23
|
|
pubmed:abstractText |
The molecular characteristics associated with the response to treatment in glioblastomas (GBMs) remain largely unknown. We performed a retrospective study to assess the genomic characteristics associated with the response of GBMs to either first-line chemotherapy or radiation therapy. The gene expression (n = 56) and genomic profiles (n = 67) of responders and non-responders to first-line chemotherapy or radiation therapy alone were compared on Affymetrix Plus 2 gene expression arrays and BAC CGH arrays.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1476-4598
|
|
pubmed:author |
pubmed-author:BergerFrançoisF,
pubmed-author:ChinotOlivierO,
pubmed-author:ChneiweissHervéH,
pubmed-author:ColinCaroleC,
pubmed-author:DelattreJean-YvesJY,
pubmed-author:DucrayFrançoisF,
pubmed-author:Figarella-BrangerDominiqueD,
pubmed-author:HonnoratJérômeJ,
pubmed-author:IdbaihAhmedA,
pubmed-author:Karayan-TaponLucieL,
pubmed-author:MarieYannickY,
pubmed-author:RickmanDavidD,
pubmed-author:SansonMarcM,
pubmed-author:ThomasEmilieE,
pubmed-author:ValletteFrançoisF,
pubmed-author:WagerMichelM,
pubmed-author:de ReynièsAurélienA
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
234
|
|
pubmed:meshHeading |
pubmed-meshheading:20822523-Antineoplastic Agents, Alkylating,
pubmed-meshheading:20822523-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:20822523-DNA Methylation,
pubmed-meshheading:20822523-Glioblastoma,
pubmed-meshheading:20822523-Humans,
pubmed-meshheading:20822523-Immunohistochemistry,
pubmed-meshheading:20822523-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20822523-Promoter Regions, Genetic,
pubmed-meshheading:20822523-Retrospective Studies
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients.
|
|
pubmed:affiliation |
INSERM, U842, Lyon, F-69372 France. francois.ducray@chu-lyon.fr
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
