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rdf:type |
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lifeskim:mentions |
umls-concept:C0016360,
umls-concept:C0024487,
umls-concept:C0027627,
umls-concept:C0031327,
umls-concept:C0205210,
umls-concept:C0392752,
umls-concept:C0555952,
umls-concept:C0681842,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
2011-6-27
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pubmed:abstractText |
5-Fluorouracil remains widely used in colorectal cancer treatment more than 40 years after its development. 19F magnetic resonance spectroscopy can be used in vivo to measure 5FU's half-life and metabolism to cytotoxic fluoronucleotides. Previous studies have shown better survival associated with longer 5FU tumour half-life. This work investigated 5FU pharmacokinetics in liver metastases of colorectal cancer.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-10576716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-10699305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-10854952,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-11390270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-11669333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-14633676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-15014355,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-16707610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-16820094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-17006886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-17131325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-1913695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-19630571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-19780181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-1997177,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-2789936,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-6743508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-7779707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-7909867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-7919450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-9081391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-9515804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-9528827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20821329-9859944
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1432-0843
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-36
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pubmed:meshHeading |
pubmed-meshheading:20821329-Adult,
pubmed-meshheading:20821329-Aged,
pubmed-meshheading:20821329-Aged, 80 and over,
pubmed-meshheading:20821329-Antimetabolites, Antineoplastic,
pubmed-meshheading:20821329-Carbon Dioxide,
pubmed-meshheading:20821329-Colon,
pubmed-meshheading:20821329-Colorectal Neoplasms,
pubmed-meshheading:20821329-Disease-Free Survival,
pubmed-meshheading:20821329-Female,
pubmed-meshheading:20821329-Fluorouracil,
pubmed-meshheading:20821329-Humans,
pubmed-meshheading:20821329-Leucovorin,
pubmed-meshheading:20821329-Liver,
pubmed-meshheading:20821329-Liver Neoplasms,
pubmed-meshheading:20821329-Magnetic Resonance Imaging,
pubmed-meshheading:20821329-Magnetic Resonance Spectroscopy,
pubmed-meshheading:20821329-Male,
pubmed-meshheading:20821329-Middle Aged,
pubmed-meshheading:20821329-Oxygen,
pubmed-meshheading:20821329-Rectum,
pubmed-meshheading:20821329-Tumor Burden
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pubmed:year |
2011
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pubmed:articleTitle |
Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response?
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pubmed:affiliation |
Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 ORE, UK. dominick.mcintyre@cancer.org.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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