Linked Life Data

20819569

Source:http://linkedlifedata.com/resource/pubmed/id/20819569

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2010-9-7
pubmed:abstractText
Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia in the elderly. The two hallmark lesions in AD brain are deposition of amyloid plaques and neurofibrillary tangles (NFTs). Hypercholesteremia is one of the risk factors of AD. But its role in the pathogenesis of AD is largely unknown. The aim of this study was to investigate the relationship between hypercholesteremia and tau phosphorylation or beta-amyloid (Abeta), and evaluate the effect of atorvastatin on the level of tau phosphorylation and Abeta in the brains of rats fed with high cholesterol diet.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0366-6999
pubmed:author
pubmed:issnType
Print
pubmed:volume
123
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1864-70
pubmed:dateRevised
2011-8-2
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Inhibition of tau hyperphosphorylation and beta amyloid production in rat brain by oral administration of atorvastatin.
pubmed:affiliation
Department of Neurology, People's Hospital of Henan Province, Zhengzhou, Henan 450003, China.
pubmed:publicationType
Journal Article