Linked Life Data

20819171

Source:http://linkedlifedata.com/resource/pubmed/id/20819171

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-1-10
pubmed:abstractText
after spinal cord injury (SCI), there are many adverse factors at the lesion site such as glial scar, myelin-derived inhibitors, cell loss and deficiency of neurotrophins that impair axonal regeneration. Therefore, combination therapeutic strategies might be more effective than a single strategy for promoting functional recovery after SCI. In the present study, we investigated whether a Nogo66 receptor (NgR) vaccine, combined with neural stem cell (NSC) transplantation, could promote better functional recovery than when NgR vaccine or NSCs were used alone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1365-2990
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-55
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:20819171-Aging, pubmed-meshheading:20819171-Animals, pubmed-meshheading:20819171-Blotting, Western, pubmed-meshheading:20819171-Disease Models, Animal, pubmed-meshheading:20819171-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:20819171-Female, pubmed-meshheading:20819171-GPI-Linked Proteins, pubmed-meshheading:20819171-Humans, pubmed-meshheading:20819171-Immunohistochemistry, pubmed-meshheading:20819171-Myelin Proteins, pubmed-meshheading:20819171-Neural Stem Cells, pubmed-meshheading:20819171-Rats, pubmed-meshheading:20819171-Rats, Sprague-Dawley, pubmed-meshheading:20819171-Receptors, Cell Surface, pubmed-meshheading:20819171-Receptors, Peptide, pubmed-meshheading:20819171-Recombinant Proteins, pubmed-meshheading:20819171-Recovery of Function, pubmed-meshheading:20819171-Spinal Cord Injuries, pubmed-meshheading:20819171-Stem Cell Transplantation, pubmed-meshheading:20819171-Vaccination
pubmed:year
2011
pubmed:articleTitle
Combined NgR vaccination and neural stem cell transplantation promote functional recovery after spinal cord injury in adult rats.
pubmed:affiliation
Department of Neurobiology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't