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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-7
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pubmed:abstractText |
Advagraf is a new extended-release once-daily formulation of tacrolimus, a potent immunosuppressant widely used in renal transplantation. The aims of his study were (i) to develop a population pharmacokinetic model for once-daily tacrolimus in adult renal transplant patients; and (ii) to develop a Bayesian estimator able to reliably estimate individual pharmacokinetic parameters and exposure indices.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0312-5963
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
683-92
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pubmed:meshHeading |
pubmed-meshheading:20818834-Adult,
pubmed-meshheading:20818834-Aged,
pubmed-meshheading:20818834-Area Under Curve,
pubmed-meshheading:20818834-Bayes Theorem,
pubmed-meshheading:20818834-Cytochrome P-450 Enzyme System,
pubmed-meshheading:20818834-Delayed-Action Preparations,
pubmed-meshheading:20818834-Female,
pubmed-meshheading:20818834-Genotype,
pubmed-meshheading:20818834-Humans,
pubmed-meshheading:20818834-Immunosuppressive Agents,
pubmed-meshheading:20818834-Kidney Transplantation,
pubmed-meshheading:20818834-Male,
pubmed-meshheading:20818834-Metabolic Clearance Rate,
pubmed-meshheading:20818834-Middle Aged,
pubmed-meshheading:20818834-Models, Biological,
pubmed-meshheading:20818834-Polymorphism, Single Nucleotide,
pubmed-meshheading:20818834-Tacrolimus
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pubmed:year |
2010
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pubmed:articleTitle |
Population pharmacokinetics and Bayesian estimation of tacrolimus exposure in renal transplant recipients on a new once-daily formulation.
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pubmed:affiliation |
INSERM Unit 850, Limoges University and CHU Limoges, Limoges, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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