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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-6
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pubmed:abstractText |
The authors demonstrated previously that the combination of topotecan (TPT) and carboplatin (CBP) was more effective than current chemotherapeutic combinations used to treat retinoblastoma in an orthotopic xenograft model. However, systemic coadministration of these agents is not ideal, because both agents cause dose-limiting myelosuppression in children.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-34
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pubmed:dateRevised |
2011-10-5
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pubmed:meshHeading |
pubmed-meshheading:20818652-Animals,
pubmed-meshheading:20818652-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20818652-Carboplatin,
pubmed-meshheading:20818652-Cell Line, Tumor,
pubmed-meshheading:20818652-Conjunctiva,
pubmed-meshheading:20818652-Disease Models, Animal,
pubmed-meshheading:20818652-Humans,
pubmed-meshheading:20818652-Mice,
pubmed-meshheading:20818652-Mice, Inbred C57BL,
pubmed-meshheading:20818652-Rats,
pubmed-meshheading:20818652-Retinal Neoplasms,
pubmed-meshheading:20818652-Retinoblastoma,
pubmed-meshheading:20818652-Topotecan,
pubmed-meshheading:20818652-Visual Acuity,
pubmed-meshheading:20818652-Xenograft Model Antitumor Assays
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pubmed:year |
2011
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pubmed:articleTitle |
Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma.
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pubmed:affiliation |
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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