Source:http://linkedlifedata.com/resource/pubmed/id/20817893
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
Thirty-two 4-month-old to 19-year-old female miniature pet pigs were spayed. Uterine lesions were present in all except 8 pigs. The 24 remaining pigs had diffuse cystic endometrial hyperplasia, of which 14 had smooth muscle tumors, including leiomyomas and leiomyosarcomas, in the uterus or broad ligament. Nodular endometrial lesions-including adenocarcinomas, adenomas, and/or adenomyosis-were present in 10 pigs, 3 of which had concurrent smooth muscle tumors. Pyometra was present in 3 pigs. In uterine sections with cystic endometrial hyperplasia, adenomyosis, or adenomas, approximately 70% of epithelial nuclei expressed estrogen receptor and progesterone receptor immunohistochemically; in adenocarcinomas, expression was 20%. Regardless of malignancy, more than 50% of nuclei in smooth muscle tumors expressed estrogen receptor and progesterone receptor. Aging was associated with the development of uterine lesions in miniature pet pigs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1544-2217
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1071-5
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pubmed:meshHeading |
pubmed-meshheading:20817893-Adenocarcinoma,
pubmed-meshheading:20817893-Adenoma,
pubmed-meshheading:20817893-Animals,
pubmed-meshheading:20817893-Broad Ligament,
pubmed-meshheading:20817893-Endometrial Hyperplasia,
pubmed-meshheading:20817893-Endometrium,
pubmed-meshheading:20817893-Estrogens,
pubmed-meshheading:20817893-Female,
pubmed-meshheading:20817893-Leiomyoma,
pubmed-meshheading:20817893-Leiomyosarcoma,
pubmed-meshheading:20817893-Progesterone,
pubmed-meshheading:20817893-Pyometra,
pubmed-meshheading:20817893-Swine,
pubmed-meshheading:20817893-Swine, Miniature,
pubmed-meshheading:20817893-Swine Diseases,
pubmed-meshheading:20817893-Uterine Diseases,
pubmed-meshheading:20817893-Uterine Neoplasms,
pubmed-meshheading:20817893-Uterus
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pubmed:year |
2010
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pubmed:articleTitle |
Uterine lesions in 32 female miniature pet pigs.
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pubmed:affiliation |
Veterinary Diagnostic and Investigational Laboratory, PO Box 1389, 43 Brighton Road, Tifton, GA 31793, USA. milha@uga.com
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pubmed:publicationType |
Journal Article
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