Linked Life Data

20817073

Source:http://linkedlifedata.com/resource/pubmed/id/20817073

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-11-24
pubmed:abstractText
The thymus serves as a critical site of T-lymphocyte ontogeny and selection. Thymic infection by HIV-1 is known to disrupt thymocyte maturation by both direct and indirect means; however, the mechanism behind these effects remains poorly defined. Macrophages represent one of the most important peripheral targets of HIV-1 infection, are resident in the thymic stroma, and play a central role in thymocyte maturation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1873-2399
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1157-66
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
HIV-1 infection inhibits cytokine production in human thymic macrophages.
pubmed:affiliation
Department of Pathology and Laboratory Medicine, University of Pennsylvania, School of Medicine, 421 Curie Boulevard, Philadelphia, PA 19104, USA. rozmyslo@mail.med.upenn.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural