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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-5-3
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pubmed:abstractText |
Recreational drug (marijuana, lysergic acid diethylamide or LSD, speed, cocaine, and "other") exposures of women with primary infertility were compared with those of a matched control group of women with proven fertility. Women who reported smoking marijuana had a slightly elevated risk for infertility due to an ovulatory abnormality (RR = 1.7, 95% CI = 1.0 to 3.0). The risk was greatest among women who had used marijuana within one year of trying to become pregnant (RR = 2.1, 95% CI = 1.1 to 4.0). No consistent frequency or duration of use effects could be demonstrated, and the risk was confined to low-frequency users. Risks associated with the use of other drugs were not elevated. The risk of infertility from a tubal abnormality associated with cocaine use was greatly increased (RR = 11.1, 95% CI = 1.7 to 70.8). Our results are consistent with animal studies suggesting that smoking marijuana may cause a transient disruption of ovulatory function. The possibility that cocaine exposure influences the development of tubal infertility needs further investigation.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1044-3983
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-200
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2081252-Adult,
pubmed-meshheading:2081252-Body Temperature,
pubmed-meshheading:2081252-Cocaine,
pubmed-meshheading:2081252-Data Collection,
pubmed-meshheading:2081252-Fallopian Tube Diseases,
pubmed-meshheading:2081252-Female,
pubmed-meshheading:2081252-Humans,
pubmed-meshheading:2081252-Infertility, Female,
pubmed-meshheading:2081252-Marijuana Abuse,
pubmed-meshheading:2081252-Ovulation,
pubmed-meshheading:2081252-Risk Factors,
pubmed-meshheading:2081252-Street Drugs,
pubmed-meshheading:2081252-Substance-Related Disorders,
pubmed-meshheading:2081252-Time Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Recreational drug use and the risk of primary infertility.
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pubmed:affiliation |
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98104.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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