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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-9-21
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pubmed:abstractText |
Cerebellar corticogenesis begins with the assembly of Purkinje cells into the Purkinje plate (PP) by embryonic day 14.5 (E14.5) in mice. Although the dependence of PP formation on the secreted protein Reelin is well known and a prevailing model suggests that Purkinje cells migrate along the 'radial glial' fibers connecting the ventricular and pial surfaces, it is not clear how Purkinje cells behave in response to Reelin to initiate the PP. Furthermore, it is not known what nascent Purkinje cells look like in vivo. When and how Purkinje cells start axonogenesis must also be elucidated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3,3'-dihexadecylindocarbocyanine,
http://linkedlifedata.com/resource/pubmed/chemical/Carbocyanines,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules, Neuronal,
http://linkedlifedata.com/resource/pubmed/chemical/Corl2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Green Fluorescent Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/LIM-Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lhx1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/reelin protein
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pubmed:status |
MEDLINE
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pubmed:issn |
1749-8104
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
23
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20809939-Adenoviridae,
pubmed-meshheading:20809939-Age Factors,
pubmed-meshheading:20809939-Animals,
pubmed-meshheading:20809939-Axons,
pubmed-meshheading:20809939-Body Patterning,
pubmed-meshheading:20809939-Carbocyanines,
pubmed-meshheading:20809939-Cell Adhesion Molecules, Neuronal,
pubmed-meshheading:20809939-Cell Movement,
pubmed-meshheading:20809939-Cerebellum,
pubmed-meshheading:20809939-Embryo, Mammalian,
pubmed-meshheading:20809939-Extracellular Matrix Proteins,
pubmed-meshheading:20809939-Genetic Vectors,
pubmed-meshheading:20809939-Green Fluorescent Proteins,
pubmed-meshheading:20809939-Homeodomain Proteins,
pubmed-meshheading:20809939-LIM-Homeodomain Proteins,
pubmed-meshheading:20809939-Mice,
pubmed-meshheading:20809939-Mice, Inbred ICR,
pubmed-meshheading:20809939-Mice, Neurologic Mutants,
pubmed-meshheading:20809939-Nerve Tissue Proteins,
pubmed-meshheading:20809939-Neurogenesis,
pubmed-meshheading:20809939-Organ Culture Techniques,
pubmed-meshheading:20809939-Purkinje Cells,
pubmed-meshheading:20809939-Repressor Proteins,
pubmed-meshheading:20809939-Serine Endopeptidases,
pubmed-meshheading:20809939-Transcription Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum.
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pubmed:affiliation |
Department of Anatomy and Cell Biology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan. tmiyata@med.nagoya-u.ac.jp
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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