Source:http://linkedlifedata.com/resource/pubmed/id/20809549
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2010-9-2
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pubmed:abstractText |
Smoke, smoke-water and aerosols have a stimulatory effect on seed germination and growth vigour of many seedlings, making them potentially useful for different purposes, provided they do not pose a health risk. Therefore, the genotoxicity of two kinds of smoke-water and 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one, a variant of the most active smoke compound (3-methyl-2H-furo[2,3-c]pyran-2-one) was evaluated using the Vitotox assay. Smoke-water extracts were obtained from burning leaves: Themeda triandra (smoke-water Tt) and a mix of Themeda triandra and Passerina vulgaris (smoke-water Kb). No genotoxic effect was observed for any of the three samples. However, the three samples are toxic at the highest concentrations (3,7-dimethyl-2H-furo[2,3-c]pyran-2-one, 2 ppm; smoke-water Tt, dilutions 1 : 1, 1 : 2, 1 : 4; smoke-water Kb, dilution 1 : 1) without addition of S9 mix. Both the butenolide 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one and smoke-water Tt are also toxic at high doses in the presence of S9 (2 ppm and dilutions 1 : 1 and 1 : 2, respectively), but not smoke-water Kb. Thus, from these results, no genotoxicity of these three samples can be assumed, which is accordance with the previous tests performed with 3-methyl-2H-furo[2,3-c]pyran-2-one and a smoke-water.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3-methyl-2H-furo(2,3-c)pyran-2-one,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Furans,
http://linkedlifedata.com/resource/pubmed/chemical/Mutagens,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrans,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrones,
http://linkedlifedata.com/resource/pubmed/chemical/Smoke,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1099-1263
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2010 John Wiley & Sons, Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
596-602
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pubmed:meshHeading |
pubmed-meshheading:20809549-Animals,
pubmed-meshheading:20809549-DNA, Bacterial,
pubmed-meshheading:20809549-DNA Damage,
pubmed-meshheading:20809549-Furans,
pubmed-meshheading:20809549-Germination,
pubmed-meshheading:20809549-Microsomes, Liver,
pubmed-meshheading:20809549-Mutagenicity Tests,
pubmed-meshheading:20809549-Mutagens,
pubmed-meshheading:20809549-Pyrans,
pubmed-meshheading:20809549-Pyrones,
pubmed-meshheading:20809549-Rats,
pubmed-meshheading:20809549-Salmonella typhimurium,
pubmed-meshheading:20809549-Seeds,
pubmed-meshheading:20809549-Smoke,
pubmed-meshheading:20809549-Water
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pubmed:year |
2010
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pubmed:articleTitle |
Genotoxicity evaluation of two kinds of smoke-water and 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one.
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pubmed:affiliation |
Gentaur bvba, Kampenhout, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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