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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1991-4-29
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pubmed:abstractText |
New cephalosporin derivatives containing a benzoxazolone ring in the side acylamino chain are synthesized using chlorides of non-substituted and halogen substituted (2-benzoxazolone-3-yl) acetic acids for the acylation of the 7-aminodesacetoxy-cephalosporanic acid and 7-amino-cephalosporanic acid amino group. Some of these new compounds exhibit a biological activity higher than that of cephalexin and cephazolin against clinical strains of Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus group A and B.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0004-4172
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1030-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2080938-Anti-Bacterial Agents,
pubmed-meshheading:2080938-Bacterial Infections,
pubmed-meshheading:2080938-Cefazolin,
pubmed-meshheading:2080938-Cephalexin,
pubmed-meshheading:2080938-Cephalosporins,
pubmed-meshheading:2080938-Chemical Phenomena,
pubmed-meshheading:2080938-Chemistry,
pubmed-meshheading:2080938-Gram-Negative Bacteria,
pubmed-meshheading:2080938-Gram-Positive Bacteria,
pubmed-meshheading:2080938-Microbial Sensitivity Tests
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pubmed:year |
1990
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pubmed:articleTitle |
Synthesis and in vitro activity of new cephalosporin derivatives containing a benzoxazolone ring.
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pubmed:affiliation |
Department of Chemistry, University of Sofia, Bulgaria.
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pubmed:publicationType |
Journal Article,
Comparative Study
|