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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2010-9-2
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pubmed:abstractText |
We previously reported the anti-angiogenic activity of paeonol isolated from Moutan Cortex. In the present study, we investigated the negative effect of paeonol oxime (PO, a paeonol derivative) on basic fibroblast growth factor (bFGF)-mediated angiogenesis in human umbilical vein endothelial cells (HUVECs) (including tumor angiogenesis) and pro-survival activity in HT-1080 fibrosarcoma cell line.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e12358
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20808805-Acetophenones,
pubmed-meshheading:20808805-Animals,
pubmed-meshheading:20808805-Capillaries,
pubmed-meshheading:20808805-Cell Differentiation,
pubmed-meshheading:20808805-Cell Line, Tumor,
pubmed-meshheading:20808805-Cell Movement,
pubmed-meshheading:20808805-Cell Proliferation,
pubmed-meshheading:20808805-Chickens,
pubmed-meshheading:20808805-Chorioallantoic Membrane,
pubmed-meshheading:20808805-Down-Regulation,
pubmed-meshheading:20808805-Endothelial Cells,
pubmed-meshheading:20808805-Fibroblast Growth Factor 2,
pubmed-meshheading:20808805-Fibrosarcoma,
pubmed-meshheading:20808805-Humans,
pubmed-meshheading:20808805-Neovascularization, Pathologic,
pubmed-meshheading:20808805-Oximes,
pubmed-meshheading:20808805-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:20808805-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20808805-Signal Transduction,
pubmed-meshheading:20808805-Umbilical Veins,
pubmed-meshheading:20808805-Vascular Endothelial Growth Factor A
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pubmed:year |
2010
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pubmed:articleTitle |
Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells.
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pubmed:affiliation |
College of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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