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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-9-2
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pubmed:abstractText |
Werner syndrome is an autosomal recessive disease of premature aging caused by a polymorphic C1367T mutation in the Werner (WRN) gene. Although there are differences between the pathobiology of normal aging and the phenotype of Werner syndrome, the clinical age-related changes are similar. The aim of the study was to investigate the incidence of the C1367T (rs1346044) polymorphism in patients with age-related cataract.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1771-5
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pubmed:meshHeading |
pubmed-meshheading:20808731-Aged,
pubmed-meshheading:20808731-Aged, 80 and over,
pubmed-meshheading:20808731-Aging,
pubmed-meshheading:20808731-Alleles,
pubmed-meshheading:20808731-Base Sequence,
pubmed-meshheading:20808731-Cataract,
pubmed-meshheading:20808731-DNA Mutational Analysis,
pubmed-meshheading:20808731-Exodeoxyribonucleases,
pubmed-meshheading:20808731-Female,
pubmed-meshheading:20808731-Genetic Predisposition to Disease,
pubmed-meshheading:20808731-Humans,
pubmed-meshheading:20808731-Israel,
pubmed-meshheading:20808731-Male,
pubmed-meshheading:20808731-Middle Aged,
pubmed-meshheading:20808731-Molecular Sequence Data,
pubmed-meshheading:20808731-Polymorphism, Single Nucleotide,
pubmed-meshheading:20808731-RecQ Helicases
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pubmed:year |
2010
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pubmed:articleTitle |
Lack of association of the WRN C1367T polymorphism with senile cataract in the Israeli population.
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pubmed:affiliation |
Department of Ophthalmology, Rabin Medical Center, Petach Tikva, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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