Linked Life Data

2080350

Source:http://linkedlifedata.com/resource/pubmed/id/2080350

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1991-4-26
pubmed:abstractText
Autologous transplantation of the superior cervical ganglion (SCG) into the caudate nuclei of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian monkey was studied in regard to animal behavior and catecholamine (CA) metabolites in cerebrospinal fluid. Monkeys which had undergone autotransplantation of the SCG revealed an apparent improvement in motor activity. The homovanillic acid content in cerebrospinal fluid increased following the SCG transplantation and was correlated with an increase in motor activity. CA histofluorescence studies confirmed the long-term survival of the SCG graft in which many CA fibers and cells were observed. The present experiment indicates that dopamine released from the graft improved the symptoms of parkinsonism in the monkey.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1011-6125
pubmed:author
pubmed:issnType
Print
pubmed:volume
54-55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
337-41
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Transplantation of autologous superior cervical ganglion into the brain of parkinsonian monkeys.
pubmed:affiliation
Department of Neurological Surgery, Wakayama Medical College, Japan.
pubmed:publicationType
Journal Article