Linked Life Data

20802354

Source:http://linkedlifedata.com/resource/pubmed/id/20802354

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
2010-9-15
pubmed:abstractText
Perturbation of cochlear microcirculation, that is, ischemia is a major cause of hearing impairment. Earlier studies examined the short-term (?7 days) effect of cochlear ischemia. This study characterized the long-term (4 weeks) functional and morphological changes in adult guinea pig cochleae subject to transient ischemia by clamping the labyrinthine artery for 0.25-3?h. Notably, cochlear ischemia for over 1?h caused an increase of auditory brainstem response thresholds and loss of high-frequency hearing, basal-turn hair cells, and spiral ganglions. Auditory recovery may be possible after 30-min ischemia. The extent of the functional and morphological changes depended on the ischemia period, and the changes progressed in extent from the apical to the basal turn in an orderly fashion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1473-558X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
27
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
968-75
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Changes in guinea pig cochlea after transient cochlear ischemia.
pubmed:affiliation
Department of Otolaryngology-Head and Neck Surgery, China Medical University Hospital, North District, Taichung City, Taiwan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't