Linked Life Data

20800620

Source:http://linkedlifedata.com/resource/pubmed/id/20800620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-10-11
pubmed:abstractText
Reach-to-grasp tasks have been used to study rodent models of motor system damage, stroke, and neurodegenerative disorders such as Parkinson's. These tasks are especially useful as they allow evaluation of bilateral or unilateral damage in different regions of the brain. Performing reach-to-grasp tests in juvenile mice may be important to understand motor disorders of early onset. This study evaluated the performance of juvenile and adolescent mice on a reach-to-grasp task. Male and female C57BL/6J mice (n=93) were tested in a forelimb reaching task at postnatal weeks 4, 5, 7, 9 and 12. At all ages mice could learn the task and improved performance with training. Results show that reach-to-grasp tasks can be used to study skill learning in juvenile and adolescent mice. Results are discussed in terms of adapting methodologies (test protocols and arenas) when performing behaviour tests in young mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1872-678X
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
30
pubmed:volume
193
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
82-5
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Performance of juvenile mice in a reach-to-grasp task.
pubmed:affiliation
Laboratory Animal Science, Institute for Molecular & Cell Biology, Porto, Portugal. jmarques@ibmc.up.pt
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't