Linked Life Data

20798580

Source:http://linkedlifedata.com/resource/pubmed/id/20798580

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-8-27
pubmed:abstractText
In an ongoing investigation of compounds from natural products that exhibit anti-aging properties, hydroxyhibiscone A (1), a new furanosesquiterpenoid, together with hibiscone D (2), was isolated from the root bark of Hibiscus syriacus. Utilizing UV, IR, NMR, and MS spectroscopic analyses, these chemical structures were revealed. Compounds 1 and 2 were found to possess significant anti-aging properties on the human neutrophil elastase (HNE) assay, exhibiting HNE inhibitory activities with IC50 values of 5.2 and 4.6 micronM, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1017-7825
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1189-91
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Hydoroxyhibiscone A, a novel human neutrophil elastase inhibitor from Hibiscus syriacus.
pubmed:affiliation
Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't