Source:http://linkedlifedata.com/resource/pubmed/id/20798009
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-12-14
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pubmed:abstractText |
There is great interest in evaluating gene-environment interactions with chemical exposures, but exposure assessment poses a unique challenge in case-control studies. Expert assessment of detailed work history data is usually considered the best approach, but it is a laborious and time-consuming process. We set out to determine if a less intensive method of exposure assessment (a job exposure matrix (JEM)) would produce similar results to a previous analysis that found evidence of effect modification of the association between expert-assessed lead exposure and risk of brain tumours by a single nucleotide polymorphism in the ALAD gene (rs1800435).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1470-7926
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4-9
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pubmed:meshHeading |
pubmed-meshheading:20798009-Adult,
pubmed-meshheading:20798009-Brain Neoplasms,
pubmed-meshheading:20798009-Epidemiologic Methods,
pubmed-meshheading:20798009-Genetic Predisposition to Disease,
pubmed-meshheading:20798009-Genotype,
pubmed-meshheading:20798009-Glioma,
pubmed-meshheading:20798009-Humans,
pubmed-meshheading:20798009-Lead,
pubmed-meshheading:20798009-Meningioma,
pubmed-meshheading:20798009-Occupational Diseases,
pubmed-meshheading:20798009-Occupational Exposure,
pubmed-meshheading:20798009-Polymorphism, Single Nucleotide,
pubmed-meshheading:20798009-Porphobilinogen Synthase
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pubmed:year |
2011
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pubmed:articleTitle |
Comparison of occupational exposure assessment methods in a case-control study of lead, genetic susceptibility and risk of adult brain tumours.
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pubmed:affiliation |
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. pbhatti@fhcrc.org
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pubmed:publicationType |
Journal Article,
Comparative Study,
Multicenter Study,
Research Support, N.I.H., Intramural
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