Linked Life Data

2077845

Source:http://linkedlifedata.com/resource/pubmed/id/2077845

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1991-4-19
pubmed:abstractText
Early changes in intracranial pressure (ICP) and mean arterial blood pressure (MABP) were studied in normotensive and spontaneously hypertensive (SHR) Wistar rats after the development of an experimental intracerebral haemorrhage (ICH). The volume of the ICH was 200 or 400 microliters and they were located in the nucleus caudatus or the subcortical area of the occipital lobe. Our study shows that 200 microliters ICH produced both in normotensive and SHR rats similar mortality rates and ICP changes. However, 400 microliters ICH lead to a significantly higher mortality in SHR rats. The systemic hypertensive response to the increasing of ICP was not observed in SHR animals. Thus, the increase in the cerebral pressure perfusion measured in normal rats does not happen in SHR rats. The cause of this fact in SHR rats could be due to local factors or related to alterations in the peripheral part of the vasomotor reflex.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-6268
pubmed:author
pubmed:issnType
Print
pubmed:volume
107
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
102-7
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Experimental intracerebral haemorrhage in normotensive and spontaneously hypertensive rats.
pubmed:affiliation
Department of Neurosurgery, Faculty of Medicine, University of Cádiz, Spain.
pubmed:publicationType
Journal Article