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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1991-4-22
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pubmed:abstractText |
We recorded the neuronal activity of the medial region of the septum (MS-DB) intracellularly in guinea-pig septal slices. Electrical stimulation of the diagonal band (DB) evoked a low-threshold initial period of inhibition in the cells (20-280 msec in various cells). When the intensity of the stimulation was increased, this inhibitory phase shortened gradually or in a step-wise fashion, remaining unaltered in a portion of the cells with brief (40-50 msec) inhibition. The duration of the inhibition stabilized within a range of 30-60 msec. Many cells with single-spike background activity switched to generating post-inhibitory bursts at various levels of stimulation by current. Cells of the MS-DB with background rhythmical bursts always responded by phase locking to the stimulus. As a result, 58% of all of the cells of the MS-DB generated relatively short-latency, synchronized bursts when the level of afferent inflow was increased.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0097-0549
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
437-45
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2077446-Animals,
pubmed-meshheading:2077446-Brain,
pubmed-meshheading:2077446-Electric Stimulation,
pubmed-meshheading:2077446-Guinea Pigs,
pubmed-meshheading:2077446-Hippocampus,
pubmed-meshheading:2077446-Medial Forebrain Bundle,
pubmed-meshheading:2077446-Models, Biological,
pubmed-meshheading:2077446-Neurons, Afferent,
pubmed-meshheading:2077446-Theta Rhythm
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pubmed:articleTitle |
Modelling the regulation of theta-rhythm by increasing afferent inflow in septal slices.
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pubmed:affiliation |
Institute of Biological Physics, Pushchino.
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pubmed:publicationType |
Journal Article,
In Vitro
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