Linked Life Data

2075399

Source:http://linkedlifedata.com/resource/pubmed/id/2075399

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1991-4-15
pubmed:abstractText
The authors have studied the synthesis of interleukin 1 by articular and circulating macrophages and the effect of two types of interferon alpha (IF) on this synthesis in 20 patients with untreated rheumatoid arthritis (RA). The articular and especially systemic interleukin levels in the RA patients are significantly higher than those of the test subjects. Interferon modifies in a very different way the production of interleukin 1 in the patients and in the test subjects. This is linked with the in vitro experimental conditions as well as the increase in the IL1 levels in the patients. The authors discuss the perspective therapeutics offered by this modulation of interleukin production by interferon.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0035-2659
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
627-31
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Immunomodulator effects of 2 kinds of interferon alpha on the in vitro synthesis of systemic and articular interleukin 1 in rheumatoid polyarthritis].
pubmed:affiliation
Service de Microbiologie, Faculté de Médecine, Craiova, Roumanie.
pubmed:publicationType
Journal Article, In Vitro, English Abstract