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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1991-4-16
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pubmed:abstractText |
Conventional methods for vascular access and bile collection in the rat, such as the isolated perfused liver, study under anesthesia, and animal restraint, do not allow study of a physiologically intact rat. A simple technique for vascular access and monitoring of biliary secretions in the intact, unrestrained, unanesthetized rat for extended periods of time is described. Sample experiments demonstrated a 20% complication rate and an 85% 24-hour survival. This model may prove useful in studies requiring chronic vascular and visceral catheterization in the awake rat.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0031-9384
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
539-42
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2075205-Anesthesia,
pubmed-meshheading:2075205-Animals,
pubmed-meshheading:2075205-Bile,
pubmed-meshheading:2075205-Biliary Tract,
pubmed-meshheading:2075205-Blood Vessels,
pubmed-meshheading:2075205-Catheterization,
pubmed-meshheading:2075205-Male,
pubmed-meshheading:2075205-Models, Biological,
pubmed-meshheading:2075205-Rats,
pubmed-meshheading:2075205-Rats, Inbred Strains,
pubmed-meshheading:2075205-Restraint, Physical
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pubmed:year |
1990
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pubmed:articleTitle |
A model for biliary and vascular access in the unanesthetized, unrestrained rat.
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pubmed:affiliation |
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|