|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
1991-4-16
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|
pubmed:abstractText |
The synthetic peptide (NANP)40, reproducing the tandem-repeated epitope of the circumsporozoite protein of Plasmodium (Laverania) falciparum, was entrapped into murine, autologous erythrocytes by a hypotonic dialysis method. Mice immunized intravenously with minute amounts of encapsulated peptide produced considerable antibody titres. This result indicates that intraerythrocytic antigen administration may have a potential as an immunization system for humans, since it dispenses with adjuvants and carrier molecules.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0020-7519
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
20
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
1109-11
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:2074141-Animals,
pubmed-meshheading:2074141-Antibodies, Protozoan,
pubmed-meshheading:2074141-Antigens, Protozoan,
pubmed-meshheading:2074141-Erythrocytes,
pubmed-meshheading:2074141-Immunization,
pubmed-meshheading:2074141-Mice,
pubmed-meshheading:2074141-Mice, Inbred C57BL,
pubmed-meshheading:2074141-Plasmodium falciparum,
pubmed-meshheading:2074141-Protozoan Proteins
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
Intraerythrocytic administration of a synthetic Plasmodium antigen elicits antibody response in mice, without carrier molecules or adjuvants.
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|
pubmed:affiliation |
Dipartimento di Biologia Molecolare, Universita' di Camerino, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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