rdf:type |
|
lifeskim:mentions |
umls-concept:C0018296,
umls-concept:C0018957,
umls-concept:C0080096,
umls-concept:C0205548,
umls-concept:C0441655,
umls-concept:C0597360,
umls-concept:C0805732,
umls-concept:C0851285,
umls-concept:C1334117,
umls-concept:C1335960,
umls-concept:C1366753,
umls-concept:C1548425,
umls-concept:C1710082
|
pubmed:dateCreated |
2010-9-10
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pubmed:abstractText |
RhoH is a constitutively active member of the family of Rho GTPases. Its expression is restricted to the haematopoietic lineage, where it serves as a positive regulator for T cell selection and mast cell function and as a negative regulator for growth-related functions in other lineages. Here, we examined the activation of signal transducer and activator of transcription (STAT) proteins in response to stimulation with interleukin 3 (IL3).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-3,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-3,
http://linkedlifedata.com/resource/pubmed/chemical/RhoH protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/STAT Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/rho GTP-Binding Proteins
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pubmed:status |
MEDLINE
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pubmed:issn |
1476-4598
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225
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pubmed:meshHeading |
pubmed-meshheading:20738848-Animals,
pubmed-meshheading:20738848-Cell Line,
pubmed-meshheading:20738848-Cell Proliferation,
pubmed-meshheading:20738848-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:20738848-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:20738848-Interleukin-3,
pubmed-meshheading:20738848-Mice,
pubmed-meshheading:20738848-Receptors, Interleukin-3,
pubmed-meshheading:20738848-STAT Transcription Factors,
pubmed-meshheading:20738848-Signal Transduction,
pubmed-meshheading:20738848-Transcription Factors,
pubmed-meshheading:20738848-Up-Regulation,
pubmed-meshheading:20738848-rho GTP-Binding Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression.
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pubmed:affiliation |
Department für Infektiologie, Medizinische Mikrobiologie und Hygiene, Ruprecht-Karls-Universität, Im Neuenheimer Feld 324, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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