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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
2010-12-7
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pubmed:abstractText |
One-carbon metabolism plays a critical role in DNA methylation and DNA synthesis. Variants of genes involved in one-carbon metabolism may result in aberrant methylation and/or DNA synthesis inhibition, and ultimately modulate the initiation and progression of tumors. In this study, the authors hypothesized that polymorphisms in one-carbon metabolism-related genes may contribute to the prognosis of nonsmall cell lung cancer (NSCLC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5700-9
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pubmed:meshHeading |
pubmed-meshheading:20737570-Asian Continental Ancestry Group,
pubmed-meshheading:20737570-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20737570-DNA Methylation,
pubmed-meshheading:20737570-Female,
pubmed-meshheading:20737570-Ferredoxin-NADP Reductase,
pubmed-meshheading:20737570-Genotype,
pubmed-meshheading:20737570-Humans,
pubmed-meshheading:20737570-Lung Neoplasms,
pubmed-meshheading:20737570-Male,
pubmed-meshheading:20737570-Methylenetetrahydrofolate Dehydrogenase (NADP),
pubmed-meshheading:20737570-Middle Aged,
pubmed-meshheading:20737570-Polymorphism, Single Nucleotide,
pubmed-meshheading:20737570-Prognosis,
pubmed-meshheading:20737570-Tetrahydrofolate Dehydrogenase
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic variants in one-carbon metabolism-related genes contribute to NSCLC prognosis in a Chinese population.
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pubmed:affiliation |
Department of Epidemiology and Biostatistics, Cancer Center, Nanjing Medical University, Nanjing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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