Linked Life Data

20736797

Source:http://linkedlifedata.com/resource/pubmed/id/20736797

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-8-25
pubmed:abstractText
Because P188 poloxamer is effective in promoting cell survival in models of acute trauma, the objectives were to understand the mechanism of its action focusing on glycogen synthase kinase-3 (GSK3) activation, interleukin-6 (IL-6), and p38 signaling.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1531-2291
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
571-6
pubmed:meshHeading
pubmed-meshheading:20736797-Ankle Injuries, pubmed-meshheading:20736797-Ankle Joint, pubmed-meshheading:20736797-Apoptosis, pubmed-meshheading:20736797-Cartilage, Articular, pubmed-meshheading:20736797-Chondrocytes, pubmed-meshheading:20736797-Enzyme Inhibitors, pubmed-meshheading:20736797-Fractures, Cartilage, pubmed-meshheading:20736797-Glycogen Synthase Kinase 3, pubmed-meshheading:20736797-Humans, pubmed-meshheading:20736797-Imidazoles, pubmed-meshheading:20736797-Interleukin-6, pubmed-meshheading:20736797-Poloxamer, pubmed-meshheading:20736797-Pyridines, pubmed-meshheading:20736797-Signal Transduction, pubmed-meshheading:20736797-Surface-Active Agents, pubmed-meshheading:20736797-Talus, pubmed-meshheading:20736797-Wound Healing, pubmed-meshheading:20736797-p38 Mitogen-Activated Protein Kinases
pubmed:year
2010
pubmed:articleTitle
Protective effect of P188 in the model of acute trauma to human ankle cartilage: the mechanism of action.
pubmed:affiliation
Department of Biochemistry, Rush University Medical Center, Chicago, IL 60612, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural