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rdf:type |
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lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0030705,
umls-concept:C0032529,
umls-concept:C0182158,
umls-concept:C0332307,
umls-concept:C0332568,
umls-concept:C0681842,
umls-concept:C1421996,
umls-concept:C1425478,
umls-concept:C1527148,
umls-concept:C1704436
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pubmed:dateCreated |
2010-9-14
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pubmed:abstractText |
Recent data indicate that loss-of-function mutation in the gene encoding the facilitative glucose transporter GLUT10 (SLC2A10) causes arterial tortuosity syndrome via upregulation of the TGF-? pathway in the arterial wall, a mechanism possibly causing vascular changes in diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
126
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pubmed:meshHeading |
pubmed-meshheading:20735855-Aged,
pubmed-meshheading:20735855-Diabetes Mellitus, Type 2,
pubmed-meshheading:20735855-Diabetic Angiopathies,
pubmed-meshheading:20735855-Female,
pubmed-meshheading:20735855-Genotype,
pubmed-meshheading:20735855-Glucose Transport Proteins, Facilitative,
pubmed-meshheading:20735855-Haplotypes,
pubmed-meshheading:20735855-Humans,
pubmed-meshheading:20735855-Longitudinal Studies,
pubmed-meshheading:20735855-Male,
pubmed-meshheading:20735855-Middle Aged,
pubmed-meshheading:20735855-Odds Ratio,
pubmed-meshheading:20735855-Peripheral Vascular Diseases,
pubmed-meshheading:20735855-Polymorphism, Single Nucleotide,
pubmed-meshheading:20735855-Risk,
pubmed-meshheading:20735855-Risk Factors,
pubmed-meshheading:20735855-Transforming Growth Factor beta
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pubmed:year |
2010
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pubmed:articleTitle |
SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes.
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pubmed:affiliation |
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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