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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-9-9
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pubmed:abstractText |
We previously showed that the envelope (env) sequence of a human endogenous retrovirus (HERV)-W locus on chromosome Xq22.3 is transcribed in human peripheral blood mononuclear cells. The env open reading frame (ORF) of this locus is interrupted by a premature stop at codon 39, but otherwise harbors a long ORF for an N-terminally truncated 475 amino acid Env protein, starting at an in-frame ATG at codon 68. We set out to characterize the protein encoded by that ORF.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1742-4690
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69
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pubmed:meshHeading |
pubmed-meshheading:20735848-Antibodies, Monoclonal,
pubmed-meshheading:20735848-Antibodies, Viral,
pubmed-meshheading:20735848-Cell Membrane,
pubmed-meshheading:20735848-Chromosomes, Human, X,
pubmed-meshheading:20735848-Codon, Nonsense,
pubmed-meshheading:20735848-Cytoplasm,
pubmed-meshheading:20735848-Endogenous Retroviruses,
pubmed-meshheading:20735848-Female,
pubmed-meshheading:20735848-Glycosylation,
pubmed-meshheading:20735848-Humans,
pubmed-meshheading:20735848-Immunohistochemistry,
pubmed-meshheading:20735848-Multiple Sclerosis,
pubmed-meshheading:20735848-Mutant Proteins,
pubmed-meshheading:20735848-Open Reading Frames,
pubmed-meshheading:20735848-Placenta,
pubmed-meshheading:20735848-Pregnancy,
pubmed-meshheading:20735848-Protein Biosynthesis,
pubmed-meshheading:20735848-Protein Sorting Signals,
pubmed-meshheading:20735848-Sequence Deletion,
pubmed-meshheading:20735848-Suppression, Genetic,
pubmed-meshheading:20735848-Transcription, Genetic,
pubmed-meshheading:20735848-Viral Envelope Proteins
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pubmed:year |
2010
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pubmed:articleTitle |
An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3.
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pubmed:affiliation |
Institut für Virologie, Gebäude 47, Universitätsklinikum des Saarlandes, 66421 Homburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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