Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Suppl
pubmed:dateCreated
2010-8-24
pubmed:abstractText
Eighty-seven hips with an infected total hip arthroplasty were treated with an antibiotic spacer and 6 weeks of antibiotics. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) measurements were repeated before attempted reimplanation, and a synovial fluid white blood cell (WBC) count was obtained intraoperatively. Nine hips (10.1%) had persistent infections. The mean ESR, CRP, and synovial fluid WBC count and differential decreased significantly (P < .001) between stages; however, the ESR remained elevated (>30 mm/h) in 50 patients (62.5%) and the CRP remained elevated (>10 mg/L) in 22 patients (27.5%) in whom the infection had been eradicated. The synovial fluid WBC count was the best test for identifying persistent infection, with an optimum cutoff of 3528 WBCs/microL(sensitivity, 78%; specificity, 96%) and an area under the curve of 0.91. The ESR and CRP were not sufficiently rigorous to aid in diagnosis and frequently failed to normalize even in patients without persistent infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1532-8406
pubmed:author
pubmed:copyrightInfo
Copyright 2010. Published by Elsevier Inc.
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-91
pubmed:meshHeading
pubmed-meshheading:20732621-Adult, pubmed-meshheading:20732621-Aged, pubmed-meshheading:20732621-Aged, 80 and over, pubmed-meshheading:20732621-Anti-Bacterial Agents, pubmed-meshheading:20732621-Arthroplasty, Replacement, Hip, pubmed-meshheading:20732621-Blood Sedimentation, pubmed-meshheading:20732621-C-Reactive Protein, pubmed-meshheading:20732621-Female, pubmed-meshheading:20732621-Hip Prosthesis, pubmed-meshheading:20732621-Humans, pubmed-meshheading:20732621-Leukocyte Count, pubmed-meshheading:20732621-Male, pubmed-meshheading:20732621-Middle Aged, pubmed-meshheading:20732621-Perioperative Care, pubmed-meshheading:20732621-Prosthesis-Related Infections, pubmed-meshheading:20732621-Reoperation, pubmed-meshheading:20732621-Sensitivity and Specificity, pubmed-meshheading:20732621-Sepsis, pubmed-meshheading:20732621-Synovial Fluid
pubmed:year
2010
pubmed:articleTitle
Perioperative testing for persistent sepsis following resection arthroplasty of the hip for periprosthetic infection.
pubmed:affiliation
Rush University Medical Center, Chicago, Illinois 60611, USA.
pubmed:publicationType
Journal Article, Evaluation Studies